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SUP3R-4 (4-DHEA) is a non-methylated (non-17a-alkylated) prohormone to.4-DHEA is one of the only prohormones left on the market today that converts to the mother of all hormones testosterone. Like 1-DHEA, 4-DHEA converts to three different powerful hormones.
It requires a 2 step conversion process involving 3b-HSD and 17b-HSD to convert it to Androstenedione/androstenediol, and then testosterone. 4-Andro is used as a test base with other PH's to combat the side effects of lethargy and libido issues. Estrogen levels can also be an issue and can effect libido, dry skin and joint pain. When using 4-Andro, you may experience a minor estrogen conversion, muscle cramps, high blood pressure, aggression and in some cases gynecomastia (gyno). Ar1macare Pro or any estrogen blocker can be used to decrease estrogen conversion and avoid gyno and other estrogen side effects. The effects can be reduced or totally prevented with the right maintenance supplement.
4-dhea has few side effects, however most noticeably will be it’s conversion to estrogen. If you experience excessive bloat, water retention, or senstivie nipples, it’s best to lower the dose or discontinue it’s use.